Join the Amoeba Sisters as they explore the action potential. This video discusses resting membrane potential before going into the phases of the action potential including vocabulary such as depolarization, repolarization, and hyperpolarization. The video also mentions different types of gated ion channels and how the action potential can be propagated.
Cell Signaling Video: https://youtu.be/-dbRterutHY?feature=shared
Sodium Potassium Pump Video: https://youtu.be/7NY6XdPBhxo?feature=shared
Table of Contents:
00:00 Intro
0:47 Excitable Cells
1:23 Ions and Travel Across Membrane
1:42 Sodium Potassium Pump
2:43 Leak Channels
3:26 Membrane Potential
4:17 Action Potential Walkthrough
7:23 Initiation and Different Gated Ion Channels
9:07 Action Potential Propagation (in Neuron)
FACTUAL REFERENCES:
Abdelsayed, Mena, and Stanislav Sokolov. “Voltage-Gated Sodium Channels.” Channels, vol. 7, no. 3, 19 May 2013, pp. 146–152, https://doi.org/10.4161/chan.24380.
Betts, J. Gordon, et al. “12.4 the Action Potential - Anatomy and Physiology 2e | OpenStax.” Openstax.org, 20 Apr. 2022, openstax.org/books/anatomy-and-physiology-2e/pages/12-4-the-action-potential.
Urry, Lisa A, et al. Campbell Biology. 11th ed., New York, Ny, Pearson Education, Inc, 2017.
Zedalis, Julianne, and John Eggebrecht. “26.2 How Neurons Communicate - Biology for AP® Courses | OpenStax.” Openstax.org, 8 Mar. 2018, openstax.org/books/biology-ap-courses/pages/26-2-how-neurons-communicate.
FURTHER READING:
More about epilepsy and medications for this condition that can target ion channels:
https://www.cdc.gov/epilepsy/index.html
https://pmc.ncbi.nlm.nih.gov/articles/PMC1852436/
https://pubmed.ncbi.nlm.nih.gov/20298965/
What about action potential in myelinated neurons?
https://www.nature.com/scitable/topicpage/myelin-a-specialized-membrane-for-cell-communication-14367205/
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