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Cardiovascular physiology - Action potential of cardiac muscle and SA Node , medical animations
Pacemaker cells (e.g., sinus node) of the conduction system of the heart autonomously and spontaneously generate an action potential that spreads throughout the myocardium.
The electrical excitation of the myocardium results in its contraction (electromechanical coupling).
The phase of relaxation prevents immediate re-excitation (refractory period).
Conducting system of the heart
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See structures of cardiac conduction system: collection of nodes and specialized myocytes that initiate and coordinate contraction of the heart muscle
Normal course of electrical conduction: sinus node (pacemaker) creates an action potential โ signal spreads across atria and causes their contraction โ signal reaches AV node and is slowed down โ AV node conducts the signal to bundle of His down the interventricular septum to Purkinje fibers in myocardium โ they spread the signal across the ventricles โ the ventricles contract (electromechanical coupling)
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