Animation is a whole thing, but before you can make any animations for your game, you're going to need to rig your characters. Lucky for you, in most cases you'll be able to get a very powerful rig within minutes due to blender rigify add-on!
Use the same base mesh as me from here : https://www.cgtrader.com/free-3d-models/character/man/base-mesh-spider-man
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gameplay channel : https://www.youtube.com/channel/UCh7-Gdfn4hLzD23fTMjVNSw