EDIT: 3/13/21, I uploaded a new version of this video that has more information and is hopefully more concise. Feel free to keep watching/referring to this one if you prefer it, though. :)
My WAs used: https://wago.io/p/FastCats
This video is for those who want to learn how to set up VuhDo and tweak it to suit their playstyle/aesthetic taste. This is a casual guide and moves slowly so that you can follow along while viewing if you like!
Edit 1/4/21: See my reply to the pinned comment to learn how to manage debuffs a bit. :) You can turn them on under Debuffs - Standard - Uncheck everything but "Icon." Doing this will show debuffs on your panels as well.
If you'd prefer a simpler explanation of how to set the add-on up right out of the box to begin playing, please see my other video (while it is intended for Classic WoW, if you ignore the parts about spell ranks it is still applicable to retail): https://www.youtube.com/watch?v=mnk4Xtp_2Xg
Timestamps to guide your way:
0:00, Introduction/What Is VuhDo?
4:10, Cleaning up the default VuhDO UI
6:10, Introduction to Sizing
7:45, Setting up and Testing for Full Raid Group
8:45, Getting rid of/moving the pet panel and remaking it Your Way
10:27, Headers and Sizing for Panels
13:46, Text editing
14:57, HoT Icon Setup!
16:23, Setting up actual click-healing!
19:21, How to make HoT icons more visible + how to get rid of the Giant Red Dot (druids only)/how to remove or change the role icon size
22:06, Test showing all HoT icons working/what they should look like
23:58, Smart Cast & dispelling
25:14, Adjusting the pet panel size
26:01, Tips on how you can use VuhDo + clips of me healing leveling PuG dungeons on various alts
Addons I use (that you can probably see in this video):
-VuhDo (of course!)
-Shadowed Unit Frames
-Dominos -Chatter
-WeakAuras (mine were inspired by Growl You can find him here: https://www.youtube.com/channel/UCwxbtziyebIaVN2XS0wVITQ !)
-TotalRP3
-Recount
-HearKitty (audio cues for combo points/holy power/etc)