Introduction into data analysis for mass spectrometry-based proteomics - Lecture by Lennart Martens

A broad introduction into mass spectrometry-based proteomics data analysis. Slides: https://drive.google.com/file/d/1JKiIOlkPrH2kF7kR74SDytcOFhDhmKEy/view Chapters: 0:00 Introduction 7:46 Amino acids, peptides, and proteins 27:46 Mass spectrometry basics 01:20:44 MS/MS spectra and identification 01:34:33 Database search algorithms in three phases 02:20:31 Sequential search algorithms 02:25:56 Decoys and false discovery rate calculation 02:37:51 Protein inference: Bad, ugly, and not so good By Prof. Dr. Lennart Martens, as part Prof. Dr. Clement's Statistical Genomics course from the Master of Science in Bioinformatics program at Ghent University. @statomics @universiteitgent @VIBinFlanders CC BY-SA 4.0 You are free to: - Share — copy and redistribute the material in any medium or format - Adapt — remix, transform, and build upon the material for any purpose, even commercially. Under the following terms: - Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. - ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original. https://creativecommons.org/licenses/by-sa/4.0/