On February 14th, 2025, Drs. Elizabeth Chen, Hamish Fraser, and Neil Sarkar presented on “Leveraging EHRs and AI to Advance Biomedical Discovery and Healthcare Delivery.” In this panel presentation, an overview of research, education, and service activities was provided for the Brown Center for Biomedical Informatics, which provide leadership and operational support for the BIBCE Core. Examples of projects in BCBI research labs involving the use of EHR data, application of AI methods such as machine learning and natural language processing, and development and evaluation of AI-based clinical decision support tools in EHR systems were also provided.