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Metabolism of Histidine and Lysine || Metabolism of Basic Amino Acids || NEET PG || Biochemistry

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This video is on the metabolism of Histidine and Lysine which are basic amino acid. Histidine is basic and nutritionally semi-essential amino acid Histidine has an imidazole ring. Its pK value is 6.1; and hence in proteins, histidine is responsible for the maximum buffering action Importance of Histidine 1.Synthesis of histamine – - Mediator of allergic reactions - Potent vasodilator - Increases the secretion of gastric juice Metabolism of Lysine Lysine is a nutritionally essential amino acid. Lysine is ketogenic amino acid. Its deficient in cereals It contains two amino groups, neither of which can undergo direct transamination.

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