In this video, Dr. Doug Lucas discusses the use of Evenity (Romosozumab) in treating osteoporosis, highlighting its mechanism of action, efficacy, and safety concerns. He reviews clinical trial data, including the FRAME, ARCH, and STRUCTURE studies, to illustrate the drug's impact on bone density and fracture risk. Dr. Doug emphasizes the importance of understanding both relative and absolute risk reductions, as well as the cardiovascular risks associated with Evenity. He concludes with practical recommendations for its use in clinical practice, stressing the need for careful patient assessment.
*STUDIES*
https://www.nejm.org/doi/10.1056/NEJMoa1607948?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200www.ncbi.nlm.nih.gov
https://pubmed.ncbi.nlm.nih.gov/28892457/
https://pubmed.ncbi.nlm.nih.gov/28755782/
https://academic.oup.com/jbmr/article-abstract/35/5/994/7500032?redirectedFrom=fulltext&login=false
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This channel is focused on Bones, Hormones, and Healthspan to help midlife women and beyond aim for optimal, not average, and reignite their spark!
The videos on this channel will be focused around helping women navigate healthspan and longevity through the lens of osteoporosis, perimenopause, and menopause. When it comes to osteoporosis and menopause providers and educators often get tunnel vision and your symptoms might get better, but if you don't keep longevity in mind, symptom improvement may come at the expense of heart and brain health.
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*ABOUT DR. DOUG LUCAS*
Dr. Doug Lucas: Owner/founder of Optimal Bone Health and Optimal Human Health. My team and I work together to create custom bone optimization plans for individuals based around supplements, hormone optimization, peptides and more in order to increase bone health and longevity!
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#osteoporosis
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*Watch and Enjoy! Dr. Doug Lucas Key Moments in this Episode*
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Chapters
00:00 Introduction to Osteoporosis Drugs and Evenity
02:50 Understanding Evenity: Mechanism and Efficacy
06:04 Clinical Trials: FRAME, ARCH, and STRUCTURE Studies
08:56 Safety Concerns and Cardiovascular Risks
11:47 Practical Applications and Recommendations for Evenity