Don't think it would be too much to say the big bang theory tv show is one of the best sitcoms we have been lucky to watch in the last two decades, aside from being funny and teaching many important life lessons. it also introduced us to some pretty interesting actors, like Kaley Cuoco, who played the female lead, Penelope Penny Hofstadter. It's been years since the show ended in May 2019 after a 12-year run, and different rumors have been flying around about Kaley Cuoco becoming completely different just five years after the show.