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Resting Membrane Potential | Neurology | Dr Najeeb
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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬
00:00:00 Introduction
00:00:45 What Is Resting Membrane Potential And Action Potential?
00:04:08 How Membrane Produce Action Potential
00:21:36 Channels Present In Cell
00:24:25 Potassium And Sodium Concentration Leading To Make Gradient
00:43:22 Explanation Through Another Condition
00:55:00 Resting Membrane Potential Explanation
01:00:04 What Is Indirect Rule?
01:04:00 If Stimulation Occurs
01:04:59 Maintaining Equilibrium
01:11:39 Equilibrium Potential Equation
01:15:07 Explanation Of Equation
01:19:30 Mr. Guyton’s Point Of View
01:21:09 Experimental Calculation
01:25:04 Explanation
01:27:34 Goldmann’s Equation
01:41:35 What Happen To RMP If Sodium Or Potassium Values Fluctuate
01:54:36 If Crush Injury/ Burn Injury Occur
01:56:08 In Sudden Renal Failure
01:59:35 In Hyperkalemia
02:01:00 Activation And Inactivation Gates
02:11:11 Sodium Concentration Effect On Resting Membrane Potential
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The resting potential of the nerve cell is because of the differences of ionic concentration, which are maintained on the two sides of the membrane by metabolic processes. If undisturbed, the system remains in a steady state, but it is not in thermodynamic equilibrium. When a molecule is dissociated into ions in a solution, and the latter is divided by a semipermeable membrane into two compartments with unequal ionic concentrations, then an electric potential difference exists between the compartments. This chapter discusses how a relationship between potential and concentration differences at equilibrium can be derived. It discusses the exchange of ions across a membrane as a more accurate derivation of the resting potential must take into account that several species are involved in ion exchange across the membranes and as it must include the different permeabilities of the membrane to the various ions.
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