Patreon:
https://www.patreon.com/primerlearning
Ageless book: https://ageless.link/
Andrew Steele on YT: https://www.youtube.com/@DrAndrewSteele
Papers and other further reading:
Diversity of aging across the tree of life: https://pmc.ncbi.nlm.nih.gov/articles/PMC4157354/
Antagonistic pleiotropy and p53: https://pmc.ncbi.nlm.nih.gov/articles/PMC2771578/
An unsolved problem of biology (Medawar): https://ia903408.us.archive.org/31/items/medawar-1952-unsolved-problem/Medawar1952-Unsolved-Problem.pdf
Evolution of the mutation rate: https://pmc.ncbi.nlm.nih.gov/articles/PMC2910838/
Our World in Data Life Expectancy explainer: https://ourworldindata.org/life-expectancy-how-is-it-calculated-and-how-should-it-be-interpreted
Other connections:
Store: https://store.dftba.com/collections/primer
Twitch: https://www.twitch.tv/justin_helps
Discord: https://discord.gg/NbruaNW
Reddit: https://www.reddit.com/r/primerlearning/
Bsky: https://bsky.app/profile/justinhelps.bsky.social
Twitter: https://twitter.com/primerlearning
Made with Godot
Github: https://github.com/Primer-Learning/PrimerTools
Music by Mathieu Keith. For business inquiries: mathieu.keith@proton.me
00:00 Introduction and outline
00:43 In which I beg for money
03:05 Simulation rules
04:09 Analyzing lifespans with no aging
09:19 Simple death genes
14:43 Mutation accumulation
26:58 Antagonistic pleiotropy
29:59 Review
30:21 Recommendations
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