In this video, I interview Lyle McDonald about his new book, 'The GLP-1 Solution'. We discuss what GLP-1s (such as Ozempic, Victoza, Wegovy, Mounjaro, Tirzepatide, Retatrutide, etc.) are, how they work, and their role in weight loss or fat loss. Lyle covers the history of weight loss drugs, the discovery and development of GLP-1 medications, and how they impact body composition, nutrition, and exercise. We also dive into key topics such as weight loss variability, side effects, long-term weight loss maintenance, and strategies for breaking plateaus.
Whether you're considering GLP-1s or just want to optimize your weight loss approach, this conversation is packed with insights from one of the most well-researched voices in the field.
Buy ‘The GLP-1 Solution’ (paperback) here: https://amzn.to/4gDbP9v
Buy ‘The GLP-1 Solution’ (Kindle edition) here: https://amzn.to/3WU0JpL
Buy Lyle’s other books here: https://store.bodyrecomposition.com/?affiliates=110
Time stamps:
0:00 Chapter 1. Introduction
2:26 Chapter 2. What is GLP-1?
4:33 2.1. The function of GLP-1
15:40 2.2 The next big step: Tirzepatide
19:45 2.3. The next next big step: Retatrutide
28:40 2.4. How GLP-1 can rectify the past failures of the health industry
30:50 Chapter 3. What is the mechanism behind the effectiveness of GLP-1?
34:33 3.1. A hidden benefit of GLP-1
41:36 3.2. Clarifying misunderstandings about the mechanism behind the effectiveness of GLP-1
50:31 3.3. On the predictors of weight loss
53:25 3.4. On why some don’t lose weight on GLP-1s
1:03:15 3.5. Expanding on some interesting GLP-1 studies
1:11:20 3.6. On the irrational case against GLP-1s
1:17:51 Chapter 4. On the side effects of GLP-1
1:18:24 4.1. Primary side effects
1:32:34 4.2. Fatal side effects
1:37:30 4.3. Mood changes
1:47:36 4.4. Ozempic face
1:49:46 4.5. Hair loss
1:50:51 4.6. Muscle loss and ozempic butt
2:08:52 Chapter 5. On weight loss maintenance with GLP-1
2:22:52 5.1. Can exercise optimize GLP-1s?
2:33:34 Chapter 6. On GLP-1 and its applications for lean athletes
2:34:06 6.1. GLP-1 usage by jiu jitsu athlete
2:34:59 6.2. GLP-1 usage among physique athletes
2:37:42 6.3. GLP-1 usage among performance athletes
2:41:08 6.4. GLP-1 usage among weight class athletes
2:42:59 6.5. GLP-1 usage among dancers and gymnasts
2:44:14 6.6. GLP-1 usage among physique athletes revisited
3:07:46 Chapter 7. Conclusion
3:08:33 Extras
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