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The Puzzle Comes Together - Why Dysfunctional Metabolism Might Explain Long Covid

Gez Medinger 47,774 3 years ago
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In this film I talk again to Dr Ade Wentzel, who has co-authored a new paper looking at the metabolic dysfunction present in Long Covid, and how it is connected to just about everything else, from endothelial dysfunction, to platelet activation and microclotting, dysautonomia, mast cell activation and even erectile dysfunction. There’s a reason no-one’s cracked it until now, and it’s because it’s bloody complicated. So this film will get a little granular at times - I’m afraid it’s kind of impossible to explain it without breaking it down to the nuts and bolts. * Please do talk to your doctor first if you have any concerns about taking any new supplements or medications of any kind. * * Note on the dosages slide, Cholecalciferol should be 10mcg, Quercetin dose should be in mg not mcg * ---------------------------------------------------------------------- The Long Covid Handbook (Oct 2022), by Gez Medinger and Professor Danny Altmann and published by Penguin Books is now available in paperback, ebook and audiobook. A singular resource that brings together everything patients, clinicians and academics have learnt about the condition since early 2020, as well as lessons from sufferers and researchers of ME/CFS and other chronic conditions. It offers world leading expert advice on understanding, managing and treating Long Covid. The Long Covid Handbook is available from the following links: US: https://a.co/d/0gvkJCU UK: https://amzn.eu/d/9KjurGb ------------------------------------------------------------------- CONTENTS: 0:00 Introduction 1:42 Developments in last 12 myths 2:34 The New Paper 3:53 Connection to Microclotting 9:11 Endotheliitis 10:25 Venous O2 sats & anaerobic metabolism 15:00 What Evidence is there? 17:02 Link to Dysautonomia & POTS 19:47 The 3D puzzle of LC 24:19 The Role of Connective Tissue 26:01 Viral Persistence 29:27 How to Treat? 32:00 What's wrong with Nicotinamide? 34:40 Ideal Research Project 36:58 Conclusion REFERENCES: The Biology of Long Covid (Dr Wentzel's first paper): https://youtu.be/C3w7skYHcSg Study on efficacy of Niacin in Long Covid: https://youtu.be/9-3V3h0ncIA

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