Thalidomide is the infamous drug at the heart of one of the world's worst drug safety catastrophes in modern medicine. And yet, more recent research is finding that thalidomide is still worth using, despite the risks. So what makes this drug that causes life-altering fetal abnormalities such a good thing?
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Sources:
https://pubmed.ncbi.nlm.nih.gov/35771402/
https://journals.sagepub.com/doi/abs/10.1177/1078155220975825?journalCode=oppa
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC540221/
https://www.dana-farber.org/newsroom/news-releases/2018/after-60-years--scientists-uncover-how-thalidomide-produced-birth-defects/
https://ar.iiarjournals.org/content/35/11/5767
https://www.accessdata.fda.gov/scripts/cder/rems/index.cfm?event=IndvRemsDetails.page&REMS=58
https://pubmed.ncbi.nlm.nih.gov/22348778/
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/cereblon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737249/
https://pubmed.ncbi.nlm.nih.gov/32125404/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265446/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931443/
https://pubmed.ncbi.nlm.nih.gov/22650377/
https://thalomidrems.com
https://fda.report/media/86286/Thalomid--Patient-Guide.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362654/
https://ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt196563303
https://www.washingtonpost.com/archive/lifestyle/wellness/2000/01/04/thalidomides-legacy/c7bc3a6e-4c22-49b1-929d-0d117f085d0e/
https://www.washingtonpost.com/wp-srv/washtech/longterm/thalidomide/keystories/patient062089.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631033/
Images:
https://commons.wikimedia.org/wiki/File:Pack_of_Thalidomide_tablets.jpg
https://www.gettyimages.com/detail/photo/closeup-pharmacist-hand-holding-medicine-box-royalty-free-image/897885148?phrase=pharmaceutical&adppopup=true
https://www.gettyimages.com/detail/photo/photo-of-the-fetus-on-an-ultrasound-scan-and-few-royalty-free-image/1297678794?adppopup=true
https://commons.wikimedia.org/wiki/File:NCP14053.jpg
https://www.gettyimages.com/detail/video/slow-motion-of-pipette-dripping-stock-footage/1405058944?adppopup=true
https://www.gettyimages.com/detail/photo/thalidomide-molecule-on-white-royalty-free-image/508726549?phrase=thalidomide&adppopup=true
https://www.gettyimages.com/detail/photo/spreading-royalty-free-image/172153877?phrase=hiv&adppopup=true
https://www.gettyimages.com/detail/photo/crohns-disease-royalty-free-image/912219418?phrase=Crohn%27s+disease&adppopup=true
https://commons.wikimedia.org/wiki/File:TNFa_Crystal_Structure.rsh.png
https://www.gettyimages.com/detail/photo/cell-attacking-a-cancer-cell-royalty-free-image/1383260152?phrase=cancer+cells+immune+system&adppopup=true
https://www.gettyimages.com/detail/illustration/step-of-angiogenesis-medical-learning-about-royalty-free-illustration/1370326138?phrase=angiogenesis&adppopup=true
https://www.gettyimages.com/detail/video/blood-cells-pulsing-down-artery-hd-stock-footage/883866318?adppopup=true
https://www.gettyimages.com/detail/video/hela-cells-in-culture-stock-footage/519856224?adppopup=true
https://www.gettyimages.com/detail/photo/cancer-malignant-cells-royalty-free-image/1372020529?phrase=cancer+treatment&adppopup=true
https://www.gettyimages.com/detail/illustration/multiple-myeloma-is-a-cancer-of-the-bone-royalty-free-illustration/881911948?phrase=myeloma&adppopup=true
https://www.gettyimages.com/detail/photo/senior-man-cant-remember-which-pill-to-take-royalty-free-image/1264979561?phrase=medication+mix+up&adppopup=true
https://www.gettyimages.com/detail/video/solving-the-test-exam-paper-choices-stock-footage/472947795?adppopup=true
https://www.gettyimages.com/detail/video/newborn-baby-and-little-hand-stock-footage/864018480?adppopup=true
https://www.gettyimages.com/detail/video/white-capsules-fall-from-a-metal-conveyor-automatic-line-stock-footage/1419962583?adppopup=true