Drug Science exists to campaign for a more rational, evidence-based approach to drug policy and drug use. It is frustrating to say the least that still, in the 21st century, the debate on drugs, both legal and illegal, is coloured by political and moral concerns, and often ignores the evidence. Through this podcast, we hope to further contribute to raising the profile of science and lived experience in public discourse, providing information on the actual harms and potential benefits of various drugs, challenging the myths that surround classification and legislation, and exploring the societal impact of drug policy that does not reflect the truth about drugs.